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Recombinant PBRM1 (613-734) protein
原价:¥3,264.30
现价:¥2,350.30
品牌:Active Motif
货号:31385
销量:143
配送:由沃鎏波洱发货,并提供售后服务
规格:100 ug
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概述货号31385
使用方法Recombinant PBRM1 (613-734) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
性能供应商Active Motif
背景Polybromo 1 (PBRM1) protein, also known as BRG1-associated factor 180 (BAF180) is the chromatin targeting subunit of the SWI/SNF-B (PBAF) chromatin remodeling complex that is involved in transcriptional activation and repression of select genes. PBRM1 targets chromatin via its six bromodomains that recognize and bind acetylated histone lysine residues. Bromodomains function as ‘readers’ of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. PBRM1 also acts as an inhibitor of cell proliferation and demonstrates tumor suppressing properties in relation to breast, liver and lung cancers.
存放说明Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
外观Recombinant PBRM1 (613-734) protein expressed in E. coli at a concentration of 2.98 mg/ml in 25 mM HEPES pH 7.5, 150 mM NaCl and 5% glycerol.