Recombinant PBRM1 (613-734) protein

　　原价：￥3,264.30

　　现价：￥2,350.30

　　品牌：Active Motif

　　货号：31385

　　销量：143

　　配送：由沃鎏波洱发货，并提供售后服务

　　规格：100 ug

　　沃鎏波洱(www.valubio.com)致力于打造亚太地区最大的、生命医学科研领域的、集进口科研试剂、耗材、仪器设备销售，品牌推广、技术服务等为一体的一站式电子商务平台，为生命医学提供专业、高效、优质服务。

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　　概述货号31385

　　使用方法Recombinant PBRM1 (613-734) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

　　性能供应商Active Motif

　　背景Polybromo 1 (PBRM1) protein, also known as BRG1-associated factor 180 (BAF180) is the chromatin targeting subunit of the SWI/SNF-B (PBAF) chromatin remodeling complex that is involved in transcriptional activation and repression of select genes. PBRM1 targets chromatin via its six bromodomains that recognize and bind acetylated histone lysine residues. Bromodomains function as ‘readers’ of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. PBRM1 also acts as an inhibitor of cell proliferation and demonstrates tumor suppressing properties in relation to breast, liver and lung cancers.

　　存放说明Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

　　外观Recombinant PBRM1 (613-734) protein expressed in E. coli at a concentration of 2.98 mg/ml in 25 mM HEPES pH 7.5, 150 mM NaCl and 5% glycerol.