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Recombinant GCN5 (726-837) protein
添加时间:2019-11-15

  Recombinant GCN5 (726-837) protein

  原价:¥3,264.30

  现价:¥2,350.30

  品牌:Active Motif

  货号:31371

  销量:169

  配送:由沃鎏波洱发货,并提供售后服务

  规格:100 ug

Recombinant GCN5 (726-837) protein

  沃鎏波洱(www.valubio.com)致力于打造亚太地区最大的、生命医学科研领域的、集进口科研试剂、耗材、仪器设备销售,品牌推广、技术服务等为一体的一站式电子商务平台,为生命医学提供专业、高效、优质服务。

  沃鎏波洱平台主营生命医学及生物科技相关的产品销售、技术服务等业务,现有600+个品牌,580万+种商品;产品覆盖免疫学、细胞生物学、分子生物学、蛋白质组学等诸多热点学科领域。沃鎏波洱平台将资源和服务进行有效整合,具备了强大的市场获取能力,凭借独特的业务模式获得资本市场青睐。

  概述货号31371

  使用方法Recombinant GCN5 (726-837) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

  性能供应商Active Motif

  背景GCN5, also known as K (lysine) acetyltransferase 2A (KAT2A), is a component of the ATAC complex, which is a complex that specifically exerts histone acetyltransferase (HAT) activity on histones H3 and H4. GCN5 acts as a histone acetyltransferase to promote transcriptional activation. In the case of HIV-1 infection, it is recruited by the viral protein TAT and regulates TAT's transactivating activity. In addition, evidence suggests GCN5 may play a role in the induction of chromatin remodeling of proviral genes. GCN5 also functions as a repressor of NFκB by promoting ubiquitination of the NFκB subunit RelA in a HAT-independent manner. GCN5 contains a bromodomain that recognizes acetylated histone lysine residues and functions as a ‘reader’ of these epigenetic histone marks to regulate chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets.

  存放说明Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

  外观100 µg of recombinant GCN5 (726-837) protein expressed in E. coli at a concentration of 4 mg/ml in 25 mM HEPES pH 7.5, 150 mM NaCl and 5% glycerol.