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Recombinant SMRT-DAD protein
添加时间:2019-11-14

  Recombinant SMRT-DAD protein

  原价:¥5,873.00

  品牌:Active Motif

  货号:31366

  销量:207

  配送:由沃鎏波洱发货,并提供售后服务

  规格:100 ug

Recombinant SMRT-DAD protein

  沃鎏波洱(www.valubio.com)致力于打造亚太地区最大的、生命医学科研领域的、集进口科研试剂、耗材、仪器设备销售,品牌推广、技术服务等为一体的一站式电子商务平台,为生命医学提供专业、高效、优质服务。

  沃鎏波洱平台主营生命医学及生物科技相关的产品销售、技术服务等业务,现有600+个品牌,580万+种商品;产品覆盖免疫学、细胞生物学、分子生物学、蛋白质组学等诸多热点学科领域。沃鎏波洱平台将资源和服务进行有效整合,具备了强大的市场获取能力,凭借独特的业务模式获得资本市场青睐。

  概述货号31366

  使用方法Recombinant SMRT-DAD is suitable for use in histone deacetylase (HDAC) assays as it is sufficient for activation of certain HDACs, including HDAC3. Use equimolar with the HDAC used in the assay.

  性能供应商Active Motif

  背景SMRT, also known as NCOR2, is a transcriptional corepressor that associates with a subset of nuclear receptors including RAR, PR, GR and TR in the absence of ligand. It is part of a large co-repressor protein complex that includes SIN3A/B and histone deacetylases HDAC1 and HDAC2. The deacetylase activating domain (DAD) functions to bind and activate histone deacetylase 3 (HDAC3) and is also required for N-CoR interaction with HDAC3 and its corepressor activity. SMRT and N-CoR mediated transcriptional corepression plays a significant role in development and metabolism and aberrant corepressor activity is associated with the pathogenesis of myeloid leukemias.

  存放说明Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

  外观100 µg of recombinant SMRT-DAD protein expressed in E. coli at a concentration of 0.49 mg/ml in 50 mM Tris pH 8.0, 150 mM NaCl, 1mM DTT and 50% glycerol.

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