CD47-Biotin, mouse 200 tests

　　原价：￥570.65

　　现价：￥427.99

　　品牌：Miltenyi/美天旎

　　货号：130-101-959

　　销量：102

　　配送：由沃鎏波洱发货，并提供售后服务

　　规格：200 tests

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　　概述货号130-101-959

　　描述Clone REA170 recognizes CD47, which is also known as integrin-associated protein. CD47 is a 50 KDa heavily glycosylated protein with an extracellular IgV domain, five transmembrane domains and a cytoplasmic tail, which exists in 4 different isoforms. The expression of CD47 varies in different tissue types depending upon the cytoplasmic tail isoform associated, for e.g the 16 amino acid form 2, is expressed in all cells of hematopoietic origin, endothelial and epithelial cells whereas 36 amino acids form 4 is expressed mainly in neurons, intestine, and testis. CD47 can interact with integrins, Thrombospondin-1 (TSP-1), cell surface gylcoproteins SIRPα and SIRPβ. Owing to these interactions, CD47 plays an important role in lymphocyte homeostasis, maturation and activation of dendritic cells, cellular transmigration and phagocytosis of cells. Additional Information: Clone REA170 displays negligible binding to Fc receptors.

　　别名Integrin-associated Protein, IAP, Itgp, CD47

　　克隆号REA170

　　同种亚型recombinant human IgG1

　　性能供应商Miltenyi

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