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CD34 Monoclonal Antibody (581), Biotin
添加时间:2019-10-29

  CD34 Monoclonal Antibody (581), Biotin

  原价:¥2,917.00

  品牌:Invitrogen

  货号:CD34-581-15

  销量:174

  配送:由沃鎏波洱发货,并提供售后服务

  规格:500 µL

CD34 Monoclonal Antibody (581), Biotin

  沃鎏波洱(www.valubio.com)致力于打造亚太地区最大的、生命医学科研领域的、集进口科研试剂、耗材、仪器设备销售,品牌推广、技术服务等为一体的一站式电子商务平台,为生命医学提供专业、高效、优质服务。

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  Product Details

  TESTED APPLICATIONSDILUTION

  Flow Cytometry (Flow)5 ul for 1x10^6 cells

  PUBLISHED APPLICATIONS

  Flow Cytometry (Flow)See 1 publications below

  Tested Species reactivityHuman

  Published species reactivityNot Applicable

  Host / IsotypeMouse / IgG1

  ClassMonoclonal

  TypeAntibody

  Clone581

  ImmunogenHuman CD34.

  ConjugateBiotin

  FormLiquid

  Concentration0.03 mg/ml

  Purificationpurified

  Storage bufferPBS with BSA

  Contains0.1% sodium azide

  Storage conditions4° C

  RRIDAB_2536503

  Background/Target Information

  CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.

  For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

  References (1)

  Have you cited this antibody in a publication? Let us know Let us know so we can reference it in this datasheet.

  Flow (1)

  The Journal of clinical investigation

  Antigen CD34+ marrow cells engraft lethally irradiated baboons.

  "CD34-581-15 was used in flow cytometry to propose that stem cells responsible for hematopoietic reconstitution are CD34+"

  Authors Berenson RJ,Andrews RG,Bensinger WI,Kalamasz D,Knitter G,Buckner CD,Bernstein ID

  Species

  Not Applicable

  Dilution

  Not Cited

  Year 1988

  Bioinformatics

  Protein Aliases: CD34; CD34 antigen; Hematopoietic progenitor cell antigen CD34; Mucosialin; RP11-328D5.2

  Gene Aliases: CD34

  UniProt ID: (Human) P28906

  Entrez Gene ID: (Human) 947

  Function(s)

  tissue homeostasis

  endothelial cell proliferation

  glomerular filtration

  endothelium development

  cell-matrix adhesion

  signal transduction

  regulation of blood pressure

  cell proliferation

  positive regulation of gene expression

  negative regulation of gene expression

  single organismal cell-cell adhesion

  hemopoiesis

  negative regulation of blood coagulation

  negative regulation of tumor necrosis factor production

  positive regulation of interleukin-10 production

  mesangial cell-matrix adhesion

  paracrine signaling

  positive regulation of odontogenesis

  negative regulation of nitric oxide biosynthetic process

  positive regulation of angiogenesis

  cell motility

  regulation of immune response

  leukocyte migration

  transdifferentiation

  vascular wound healing

  hematopoietic stem cell proliferation

  positive regulation of transforming growth factor beta production

  positive regulation of granulocyte colony-stimulating factor production

  extracellular exosome assembly

  glomerular endothelium development

  stem cell proliferation

  metanephric glomerular mesangial cell differentiation

  negative regulation of cellular response to heat

  negative regulation of cellular response to hypoxia

  negative regulation of interleukin-2 secretion

  positive regulation of glial cell-derived neurotrophic factor secretion

  negative regulation of neuron death

  positive regulation of vasculogenesis

  Process(es)

  transcription factor binding

  carbohydrate binding

  sulfate binding

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  ]

  Documents

  Manuals

  L11381 Human CD34 Antigen Monoclonal Antibodies

  Material safety data sheets (MSDS)

  CD3458115_MTR-NALT_EN.pdf