- 手机:
- 电话:
- 400-021-6808转3
- 邮箱:
- service@valubio.com
- 地址:
- 上海市徐汇区肇嘉浜路798号坤阳国际商务广场408室
CD34 Monoclonal Antibody (581), Biotin
原价:¥2,917.00
品牌:Invitrogen
货号:CD34-581-15
销量:174
配送:由沃鎏波洱发货,并提供售后服务
规格:500 µL
沃鎏波洱(www.valubio.com)致力于打造亚太地区最大的、生命医学科研领域的、集进口科研试剂、耗材、仪器设备销售,品牌推广、技术服务等为一体的一站式电子商务平台,为生命医学提供专业、高效、优质服务。
沃鎏波洱平台主营生命医学及生物科技相关的产品销售、技术服务等业务,现有600+个品牌,580万+种商品;产品覆盖免疫学、细胞生物学、分子生物学、蛋白质组学等诸多热点学科领域。沃鎏波洱平台将资源和服务进行有效整合,具备了强大的市场获取能力,凭借独特的业务模式获得资本市场青睐。
Product Details
TESTED APPLICATIONSDILUTION
Flow Cytometry (Flow)5 ul for 1x10^6 cells
PUBLISHED APPLICATIONS
Flow Cytometry (Flow)See 1 publications below
Tested Species reactivityHuman
Published species reactivityNot Applicable
Host / IsotypeMouse / IgG1
ClassMonoclonal
TypeAntibody
Clone581
ImmunogenHuman CD34.
ConjugateBiotin
FormLiquid
Concentration0.03 mg/ml
Purificationpurified
Storage bufferPBS with BSA
Contains0.1% sodium azide
Storage conditions4° C
RRIDAB_2536503
Background/Target Information
CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (1)
Have you cited this antibody in a publication? Let us know Let us know so we can reference it in this datasheet.
Flow (1)
The Journal of clinical investigation
Antigen CD34+ marrow cells engraft lethally irradiated baboons.
"CD34-581-15 was used in flow cytometry to propose that stem cells responsible for hematopoietic reconstitution are CD34+"
Authors Berenson RJ,Andrews RG,Bensinger WI,Kalamasz D,Knitter G,Buckner CD,Bernstein ID
Species
Not Applicable
Dilution
Not Cited
Year 1988
Bioinformatics
Protein Aliases: CD34; CD34 antigen; Hematopoietic progenitor cell antigen CD34; Mucosialin; RP11-328D5.2
Gene Aliases: CD34
UniProt ID: (Human) P28906
Entrez Gene ID: (Human) 947
Function(s)
tissue homeostasis
endothelial cell proliferation
glomerular filtration
endothelium development
cell-matrix adhesion
signal transduction
regulation of blood pressure
cell proliferation
positive regulation of gene expression
negative regulation of gene expression
single organismal cell-cell adhesion
hemopoiesis
negative regulation of blood coagulation
negative regulation of tumor necrosis factor production
positive regulation of interleukin-10 production
mesangial cell-matrix adhesion
paracrine signaling
positive regulation of odontogenesis
negative regulation of nitric oxide biosynthetic process
positive regulation of angiogenesis
cell motility
regulation of immune response
leukocyte migration
transdifferentiation
vascular wound healing
hematopoietic stem cell proliferation
positive regulation of transforming growth factor beta production
positive regulation of granulocyte colony-stimulating factor production
extracellular exosome assembly
glomerular endothelium development
stem cell proliferation
metanephric glomerular mesangial cell differentiation
negative regulation of cellular response to heat
negative regulation of cellular response to hypoxia
negative regulation of interleukin-2 secretion
positive regulation of glial cell-derived neurotrophic factor secretion
negative regulation of neuron death
positive regulation of vasculogenesis
Process(es)
transcription factor binding
carbohydrate binding
sulfate binding
Related Products
SuperSignal™ West Pico PLUS
FIX & PERM® Cell Permeabilization Kit
ELISA Wash Buffer (30X)
]
Documents
Manuals
L11381 Human CD34 Antigen Monoclonal Antibodies
Material safety data sheets (MSDS)
CD3458115_MTR-NALT_EN.pdf