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Human VAMP-5 Affinity Purified Polyclonal Ab (25 UG)
添加时间:2019-10-28

  Human VAMP-5 Affinity Purified Polyclonal Ab (25 UG)

  原价:¥1,334.57

  现价:¥1,000.93

  品牌:R&D Systems

  货号:AF7366-SP

  销量:244

  配送:0由沃鎏波洱发货,并提供售后服务

  规格:25 UG

  Human VAMP-5 Affinity Purified Polyclonal Ab (25 UG)

  沃鎏波洱(www.valubio.com)致力于打造亚太地区最大的、生命医学科研领域的、集进口科研试剂、耗材、仪器设备销售,品牌推广、技术服务等为一体的一站式电子商务平台,为生命医学提供专业、高效、优质服务。

  沃鎏波洱平台主营生命医学及生物科技相关的产品销售、技术服务等业务,现有600+个品牌,580万+种商品;产品覆盖免疫学、细胞生物学、分子生物学、蛋白质组学等诸多热点学科领域。沃鎏波洱平台将资源和服务进行有效整合,具备了强大的市场获取能力,凭借独特的业务模式获得资本市场青睐。

  2018年,沃鎏波洱创新推出科研经销小程序研助宝,致力于打造生物医学共享分销平台,助力服务水平和效率的快速提升,始终以正品保障为底线,帮助经销商降本增效,共同繁荣生物医学产业生态

  概述货号AF7366-SP

  别名Myobrevin; VAMP-5; vesicle-associated membrane protein 5 (myobrevin); vesicle-associated membrane protein 5

  全称Vesicle-Associated Membrane Protein 5

  反应种属Human

  应用Immunohistochemistry(5-15 µg/mL)

  目标/特异性Detects human VAMP-5 in direct ELISAs. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) VAMP-7 is observed, and less than 1% cross-reactivity with rhVAMP-1, rhVAMP-2, and rhVAMP-8 is observed.

  使用方法Immunohistochemistry: 5-15 µg/mL

  来源Sterile PBS to a final concentration of 0.2 mg/mL.

  产品组分

  性能供应商R&D Systems

  Entrez Gene IDs10791 (Human); 53620 (Mouse); 89818 (Rat)

  纯化方式Antigen Affinity-purified

  免疫原E. coli-derived recombinant human VAMP-5

  Ala2-Cys72

  Accession # O95183

  生物活性Human

  标记Unconjugated

  溶解方法Sterile PBS to a final concentration of 0.2 mg/mL.

  背景VAMP-5 (vesicle associated membrane protein 5; also myobrevin) is a member of the synaptobrevin family of proteins. Although its predicted MW is 11 kDa, it runs anomalously at 16 kDa in SDS-Page. VAMP-5 is a type IV transmembrane (TM) protein (i.e.-a type II TM protein whose C-terminus is almost completely transmembrane) that is found in both trans-Golgi and plasma membranes of myotubes (mature skeletal and cardiac muscle cells). While VAMPs are commonly associated with vesicle fusion to t-SNARE in cell membranes, VAMP-5 appears to show no such activity. Human VAMP-5 is 116 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-72) with one vSNARE coiled-coil homology domain, a 21 aa TM segment, and 23 aa C-terminal luminal domain. Over aa 1-72, human VAMP-5 shares 75% aa identity with mouse VAMP-5.

  存放说明Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

  12 months from date of receipt, -20 to -70 °C as supplied.

  1 month, 2 to 8 °C under sterile conditions after reconstitution.

  6 months, -20 to -70 °C under sterile conditions after reconstitution.

  参考文献APP Cleavage and Amyloid-beta Degradation

  ICC / IHC Images: VAMP-5

  Neuronal Lineage Markers

  Synaptic SNAREs

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